PRO Entry Report - PR:000025951

Complex Forms Complex Subunits Annotations

Ontology Information

PRO ID

PR:000025951 Show OBO stanza / PAF / GPI

PRO name

smad2-smad4-ski protein complex 1 (human)

Definition

A smad2-smad4-ski protein complex 1 with phosphorylated smad2 in human. [PRO:CNA]

PRO Category

organism-complex

Parent

PR:000025971 smad2-smad4-ski protein complex 1

Taxon

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Specific
Category	Number of Terms
organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition
PR:000025951	PR:P12755-1	ski oncogene isoform 1 (human)	hSKI/iso:1	A ski oncogene isoform 1 that is encoded in the genome of human. [PMID:2762147, PRO:CNA]
	PR:Q13485-1	mothers against decapentaplegic homolog 4 isoform 1 (human)	hSMAD4/iso:1	A smad4 isoform 1 that is encoded in the genome of human. [PRO:CNA]
	PR:000025934	smad2 isoform Long phosphorylated 1 (human)	hSMAD2/iso:Long/Phos:1	A smad2 isoform Long phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-1, Ser-465/Ser-467, MOD:00046. [PMID:8980228, PMID:9346966]

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000025951 smad2-smad4-ski protein complex 1 (human)	acts_upstream_of_or_within	GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway	PMID:10485843
PR:000025951 smad2-smad4-ski protein complex 1 (human)	located_in	GO:0005634 nucleus	PMID:10485843

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:000025951 smad2-smad4-ski protein complex 1 (human)	PMID:10485843

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