Protein Ontology Report - (SMAD2:SMAD4):2 PR:000025968 - http://purl.obolibrary.org/obo/PR_000025968

Ontology Information
PRO ID	PR:000025968 Show OBO stanza
PRO name	smad2-smad4 protein complex 2
Synonyms	PRO-short-label: EXACT: (SMAD2:SMAD4):2
Definition	A smad2-smad4 protein complex that contains smad4 and the short isoform of smad2 phosphorylated in the last two Ser residues within the SSxS C-terminal motif. [PMID:15350224]
PRO Category	complex
Parent	GO:0071144 heteromeric SMAD protein complex
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms complex 1 organism-complex 2
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All complex organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000025945 PR:P97471-1 mothers against decapentaplegic homolog 4 isoform 1 (mouse) mSMAD4/iso:1 A smad4 isoform 1 that is encoded in the genome of mouse. [PRO:CNA] 1 PR:000025943 smad2 isoform Short phosphorylated 1 (mouse) mSMAD2/iso:Short/Phos:1 A smad2 isoform Short phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046. [PRO:CNA] 2 PR:000025968 PR:000000366 smad4 isoform 1 SMAD4/iso:1 A smad4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13485-1 or a 1:1 ortholog thereof. [PRO:CNA, PRO:DAN] 1 PR:000000656 smad2 isoform Short phosphorylated 1 SMAD2/iso:Short/Phos:1 A smad2 isoform Short phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation. Example: UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046. [PMID:15630024, PMID:17074756, PMID:9873005] 2 PR:000025940 PR:Q13485-1 mothers against decapentaplegic homolog 4 isoform 1 (human) hSMAD4/iso:1 A smad4 isoform 1 that is encoded in the genome of human. [PRO:CNA] 1 PR:000025938 smad2 isoform Short phosphorylated 1 (human) hSMAD2/iso:Short/Phos:1 A smad2 isoform Short phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046. [PRO:CNA] 2

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