Protein Ontology Report - BUB1:phosphoBUB1B complex (human) PR:000035577 - http://purl.obolibrary.org/obo/PR_000035577

Ontology Information
PRO ID	PR:000035577 Show OBO stanza / GPI
PRO name	BUB1:phosphoBUB1B complex (human)
Synonyms	Other: EXACT: hBUB1:hpBUBR1 complex
Definition	A BUB1:BUB1B complex that contains a phosphorylated form of BUB1B, and whose components are encoded in the genome of human. [PMID:11792804, PRO:KER]
PRO Category	organism-complex
Parent	PR:000035578 BUB1:BUB1B complex
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-complex 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000035577 PR:O43683 mitotic checkpoint serine/threonine-protein kinase BUB1 (human) hBUB1 A mitotic checkpoint serine/threonine-protein kinase BUB1 that is encoded in the genome of human. [PMID:10749118, PMID:11030144, PMID:11792804, PMID:12719470, PMID:15190214, PMID:15525512, PMID:15592459, PMID:16760428, PMID:17671183, PMID:17785528, PMID:20016069, PMID:20624902, PMID:20703093, PRO:KER] PR:000035428 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 2 (human) hBUB1B/Phos:2 A mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form in human that has had Thr-620 phosphorylated by CDK1, and Ser-676 and/or Thr-680 phosphorylated by PLK1. Additionally, Thr-792 and/or Thr-1008 may be phosphorylated based on in vitro experiments. This phosphorylated form is observed during pro metaphase, spindle depolymerization (nocodazole), and lack of kinetochore tension (taxol). Example: UniProtKB:O60566, Thr-620, MOD:00047|(Ser-676, MOD:00046 and/or Thr-680, MOD:00047)|(Thr-792, MOD:00047 and/or Thr-1008, MOD:00047). [PMID:10593653, PMID:11030144, PMID:11792804, PMID:17276342, PMID:17376779, PMID:17785528, PMID:18440313, PMID:23079597, PRO:KER]

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