back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - Toll/interleukin-1 receptor domain-containing adapter protein
PR:000001751 - http://purl.obolibrary.org/obo/PR_000001751
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001751   
  PRO nameToll/interleukin-1 receptor domain-containing adapter protein 
  Synonyms
PRO-Short-label: EXACT:TIRAP
Gene-based: RELATED:MAL
Other: EXACT:adaptor protein Wyatt | MyD88 adapter-like protein | TIR domain-containing adapter protein
  Definition"A protein that is a translation product of the human TIRAP gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification2                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF037750
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001751 Toll/interleukin-1 receptor domain-containing adapter protein
TIRAP

Yes
organism-gene


PR:P58753 Toll/interleukin-1 receptor domain-containing adapter protein (human)
hTIRAP

Yes
organism-sequence


PR:P58753-1 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 (human)
hTIRAP/iso:1

Yes
organism-modification


PR:000027214 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1 (human)
hTIRAP/iso:1/Phos:1

Yes
organism-sequence


PR:P58753-2 Toll/interleukin-1 receptor domain-containing adapter protein isoform 2 (human)
hTIRAP/iso:2
Yes
organism-sequence


PR:P58753-3 Toll/interleukin-1 receptor domain-containing adapter protein isoform h3 (human)
hTIRAP/iso:h3

organism-modification


PR:000049460 Toll/interleukin-1 receptor domain-containing adapter protein phosphorylated 2 (human)
hTIRAP/Phos:2

organism-gene


PR:Q4PT31 disease resistance protein (TIR-NBS class) (Arabidopsis thaliana)
At-TIRAP

organism-gene


PR:Q4U127 Toll-interleukin 1 receptor domain-containing adaptor protein (chicken)
chick-TIRAP

Yes
organism-gene


PR:Q99JY1 Toll/interleukin-1 receptor domain-containing adapter protein (mouse)
mTIRAP

Yes
organism-modification


PR:000027216 Toll/interleukin-1 receptor domain-containing adapter protein phosphorylated 1 (mouse)
mTIRAP/Phos:1

Yes
sequence


PR:000027185 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1
TIRAP/iso:1

organism-sequence


PR:P58753-1 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 (human)
hTIRAP/iso:1

Yes
organism-modification


PR:000027214 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1 (human)
hTIRAP/iso:1/Phos:1

Yes
modification


PR:000027213 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1
TIRAP/iso:1/Phos:1

organism-modification


PR:000027214 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1 (human)
hTIRAP/iso:1/Phos:1

Yes
modification


PR:000027215 Toll/interleukin-1 receptor domain-containing adapter protein phosphorylated form
TIRAP/PhosRes+

modification


PR:000027213 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1
TIRAP/iso:1/Phos:1

organism-modification


PR:000027214 Toll/interleukin-1 receptor domain-containing adapter protein isoform 1 phosphorylated 1 (human)
hTIRAP/iso:1/Phos:1

Yes
organism-modification


PR:000049460 Toll/interleukin-1 receptor domain-containing adapter protein phosphorylated 2 (human)
hTIRAP/Phos:2

Back to top
TIRAP forms found in complexes   

TIRAP Component
 Complexes
PR:000001751 TIRAP PR:000025784 MYD88:TIRAP:activated TLR4 receptor
PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex
PR:000036006 TIRAP:PIP2 complex
PR:000036078 TIRAP:PIP2:activated TLR4 complex
PR:000027214 hTIRAP/iso:1/Phos:1 PR:000027218 pTIRAP:PIP2:activated TLR4 complex (human)
PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000027216 mTIRAP/Phos:1 PR:000027217 pTIRAP:PIP2:activated TLR4 complex (mouse)
PR:000037478 pTIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:P58753 hTIRAP PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
PR:000036014 TIRAP:PIP2 complex (human)
PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:P58753ZDASHZ1 hTIRAP/iso:1 PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000036135 TIRAP:PIP2:activated TLR4 complex (human)
PR:Q4U127 chick-TIRAP PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken)
PR:Q99JY1 mTIRAP PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)
PR:000027175 MYD88l:TIRAP:activated TLR4 receptor (mouse)
PR:000027187 IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse)
PR:000027196 TIRAP:PIP2:activated TLR4 (mouse)
PR:000027220 IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027221 pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027267 IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000036007 TIRAP:PIP2 complex (mouse)
PR:000037477 TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P58753-2 hTIRAP/iso:2 enablesGO:0005546 phosphatidylinositol-4,5-bisphosphate binding PMID:24529375