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Protein Ontology report - TEC-type tyrosine-protein kinase
PR:000001967 - http://purl.obolibrary.org/obo/PR_000001967
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001967   
  PRO nameTEC-type tyrosine-protein kinase 
  Synonyms
Other: EXACT:Tec family kinase
  Definition"A protein with core architecture consisting of a PH domain (Pfam:PF00169), a BTK-type zinc finger (Pfam:PF00779), an SH3 domain (Pfam:PF00018, an SH2 domain (Pfam:PF00017), and a Protein typrosine kinase domain (Pfam:PF07714)." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 10                                        
         Sequence11                                                  Organism-Sequence 17                                        
         Modification2                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF000602
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001967 TEC-type tyrosine-protein kinase
TPCN2

gene


PR:000002110 tyrosine-protein kinase BTK
BTK

organism-gene


PR:P35991 tyrosine-protein kinase BTK (mouse)
mBTK

Yes
organism-sequence


PR:P35991-1 tyrosine-protein kinase BTK isoform 1 (mouse)
mBTK/iso:1

organism-modification


PR:000037482 tyrosine-protein kinase BTK phosphorylated 1 (mouse)
mBTK/Phos:1

organism-gene


PR:Q06187 tyrosine-protein kinase BTK (human)
hBTK

organism-sequence


PR:Q06187-1 tyrosine-protein kinase BTK isoform BTK-A (human)
hBTK/iso:BTK-A

organism-sequence


PR:Q06187-2 tyrosine-protein kinase BTK isoform BTK-C (human)
hBTK/iso:BTK-C

organism-modification


PR:000044351 tyrosine-protein kinase BTK, initiator methionine removed form (human)
hBTK/InitMet-

Yes
organism-modification


PR:000046518 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 2 (human)
hBTK/InitMet-/Phos:2

organism-modification


PR:000046519 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 1 (human)
hBTK/InitMet-/Phos:1

organism-modification


PR:000045882 tyrosine-protein kinase BTK phosphorylated 1 (human)
hBTK/Phos:1

organism-modification


PR:000069637 tyrosine-protein kinase BTK deaminated 1 (human)
hBTK/Deam:1

organism-modification


PR:000070839 tyrosine-protein kinase BTK deaminated 2 (human)
hBTK/Deam:2

organism-modification


PR:000077962 tyrosine-protein kinase BTK methylated 1 (human)
hBTK/Me:1

sequence


PR:000002236 tyrosine-protein kinase BTK isoform 1
BTK/iso:1

organism-sequence


PR:P35991-1 tyrosine-protein kinase BTK isoform 1 (mouse)
mBTK/iso:1

organism-sequence


PR:Q06187-1 tyrosine-protein kinase BTK isoform BTK-A (human)
hBTK/iso:BTK-A

modification


PR:000026589 tyrosine-protein kinase BTK isoform 1, initiator methionine removed form
BTK/iso:1/InitMet-

modification


PR:000018724 tyrosine-protein kinase BTK, initiator methionine removed form
BTK/InitMet-

modification


PR:000026589 tyrosine-protein kinase BTK isoform 1, initiator methionine removed form
BTK/iso:1/InitMet-

organism-modification


PR:000044351 tyrosine-protein kinase BTK, initiator methionine removed form (human)
hBTK/InitMet-

Yes
organism-modification


PR:000046518 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 2 (human)
hBTK/InitMet-/Phos:2

organism-modification


PR:000046519 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 1 (human)
hBTK/InitMet-/Phos:1

gene


PR:000002111 tyrosine-protein kinase ITK/TSK
ITK

organism-gene


PR:P08630 tyrosine-protein kinase Btk (fruit fly)
fly-ITK

organism-sequence


PR:P08630-1 tyrosine-protein kinase Btk isoform B (fruit fly)
fly-ITK/iso:B

organism-sequence


PR:P08630-2 tyrosine-protein kinase Btk isoform A (fruit fly)
fly-ITK/iso:A

organism-gene


PR:Q03526 tyrosine-protein kinase ITK/TSK (mouse)
mITK

organism-sequence


PR:Q03526-1 tyrosine-protein kinase ITK/TSK isoform 1 (mouse)
mITK/iso:1

organism-sequence


PR:Q5STT8 tyrosine-protein kinase ITK/TSK isoform 2 (mouse)
mITK/iso:2

organism-gene


PR:Q08881 tyrosine-protein kinase ITK/TSK (human)
hITK

organism-sequence


PR:Q08881-1 tyrosine-protein kinase ITK/TSK isoform 1 (human)
hITK/iso:1

organism-modification


PR:000048074 tyrosine-protein kinase ITK/TSK phosphorylated 1 (human)
hITK/Phos:1

organism-modification


PR:000048075 tyrosine-protein kinase ITK/TSK phosphorylated 2 (human)
hITK/Phos:2

organism-modification


PR:000068201 tyrosine-protein kinase ITK/TSK cysteinylated 1 (human)
hITK/Cyst:1

organism-modification


PR:000069845 tyrosine-protein kinase ITK/TSK cysteinylated 2 (human)
hITK/Cyst:2

organism-gene


PR:Q19726 non-specific protein-tyrosine kinase (worm)
ITK (worm)

sequence


PR:000002238 tyrosine-protein kinase ITK/TSK isoform 1
ITK/iso:1

organism-sequence


PR:Q03526-1 tyrosine-protein kinase ITK/TSK isoform 1 (mouse)
mITK/iso:1

sequence


PR:000002239 tyrosine-protein kinase ITK/TSK isoform 2
ITK/iso:2

organism-sequence


PR:Q08881-1 tyrosine-protein kinase ITK/TSK isoform 1 (human)
hITK/iso:1

organism-sequence


PR:Q5STT8 tyrosine-protein kinase ITK/TSK isoform 2 (mouse)
mITK/iso:2

gene


PR:000002200 cytoplasmic tyrosine-protein kinase BMX
BMX

organism-gene


PR:P51813 cytoplasmic tyrosine-protein kinase BMX (human)
hBMX

organism-sequence


PR:P51813-1 cytoplasmic tyrosine-protein kinase BMX isoform 1 (human)
hBMX/iso:1

organism-gene


PR:P97504 cytoplasmic tyrosine-protein kinase BMX (mouse)
mBMX

organism-sequence


PR:P97504-1 cytoplasmic tyrosine-protein kinase BMX isoform 1 (mouse)
mBMX/iso:1

sequence


PR:000002323 cytoplasmic tyrosine-protein kinase BMX isoform 1
BMX/iso:1

organism-sequence


PR:P97504-1 cytoplasmic tyrosine-protein kinase BMX isoform 1 (mouse)
mBMX/iso:1

sequence


PR:000002324 cytoplasmic tyrosine-protein kinase BMX isoform 2
BMX/iso:2

organism-sequence


PR:P51813-1 cytoplasmic tyrosine-protein kinase BMX isoform 1 (human)
hBMX/iso:1

gene


PR:000002240 tyrosine-protein kinase Tec
TEC

organism-gene


PR:P24604 tyrosine-protein kinase Tec (mouse)
mTEC

organism-sequence


PR:P24604-1 tyrosine-protein kinase Tec isoform 1 (mouse)
mTEC/iso:1

organism-sequence


PR:P24604-2 tyrosine-protein kinase Tec isoform 2 (mouse)
mTEC/iso:2

organism-sequence


PR:P24604-3 tyrosine-protein kinase Tec isoform 3 (mouse)
mTEC/iso:3

organism-sequence


PR:P24604-4 tyrosine-protein kinase Tec isoform 4 (mouse)
mTEC/iso:4

organism-sequence


PR:P24604-5 tyrosine-protein kinase Tec isoform 5 (mouse)
mTEC/iso:5

organism-sequence


PR:P24604-6 tyrosine-protein kinase Tec isoform 6 (mouse)
mTEC/iso:6

organism-gene


PR:P42680 tyrosine-protein kinase Tec (human)
hTEC

organism-sequence


PR:P42680-1 tyrosine-protein kinase Tec isoform 1 (human)
hTEC/iso:1

organism-modification


PR:000049416 tyrosine-protein kinase Tec phosphorylated 1 (human)
hTEC/Phos:1

organism-modification


PR:000049417 tyrosine-protein kinase Tec phosphorylated 2 (human)
hTEC/Phos:2

sequence


PR:000002366 tyrosine-protein kinase Tec isoform 1
TEC/iso:1

organism-sequence


PR:P24604-1 tyrosine-protein kinase Tec isoform 1 (mouse)
mTEC/iso:1

organism-sequence


PR:P42680-1 tyrosine-protein kinase Tec isoform 1 (human)
hTEC/iso:1

sequence


PR:000002367 tyrosine-protein kinase Tec isoform 2
TEC/iso:2

organism-sequence


PR:P24604-2 tyrosine-protein kinase Tec isoform 2 (mouse)
mTEC/iso:2

sequence


PR:000002368 tyrosine-protein kinase Tec isoform 3
TEC/iso:3

organism-sequence


PR:P24604-3 tyrosine-protein kinase Tec isoform 3 (mouse)
mTEC/iso:3

sequence


PR:000002369 tyrosine-protein kinase Tec isoform 4
TEC/iso:4

organism-sequence


PR:P24604-4 tyrosine-protein kinase Tec isoform 4 (mouse)
mTEC/iso:4

sequence


PR:000002370 tyrosine-protein kinase Tec isoform 5
TEC/iso:5

organism-sequence


PR:P24604-5 tyrosine-protein kinase Tec isoform 5 (mouse)
mTEC/iso:5

sequence


PR:000002371 tyrosine-protein kinase Tec isoform 6
TEC/iso:6

organism-sequence


PR:P24604-6 tyrosine-protein kinase Tec isoform 6 (mouse)
mTEC/iso:6

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TPCN2 forms found in complexes   

TPCN2 Component
 Complexes
PR:000044351 hBTK/InitMet- PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:P35991 mBTK PR:000037477 TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037478 pTIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse)