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modification
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 PR:000036838 |
   NS12345
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   DenV-NS12345
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  "A dengue virus genome polyprotein proteolytic cleavage product that is derived from dengue virus genome polyprotein, N-glycosylated form and that contains the entire non-structural region of the dengue virus genome polyprotein only and is responsible for directing viral genomic RNA replication, including synthesizing negative- and positive-strand RNAs and forming the viral RNA cap structure. It consists of NS1, NS2A, NS3, NS4A, 2K, NS4B, and NS5." [PMID:1433530, PMID:22022449, PRO:ES]
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modification
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 PR:000036826 |
   NS2A-alpha
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   DenV-NS2Aalpha
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  "A dengue virus genome polyprotein proteolytic cleavage product that consists of 188 amino acids at the N-terminal end of NS2A." [PMID:23408612, PRO:ES]
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modification
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 PR:000036827 |
   NS2B
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   DenV-NS2B
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  "A dengue virus genome polyprotein proteolytic cleavage product that is a non-structural protein encoded by the dengue virus RNA genome containing a conserved hydrophilic domain necessary for protease activity in cleavage of the dengue virus genome polyprotein, N-glycosylated form." [PMID:10744671, PRO:ES]
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|  Yes |
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organism-modification
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 PR:000044761 |
   NS2B (Dengue virus 2 Thailand/NGS-C/1944)
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   NS2B (DEN2N)
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  "An NS2B in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 1346-1475." [PRO:DNx]
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 Yes | 
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modification
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 PR:000036839 |
   NS345
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   DenV-NS345
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  "A dengue virus genome polyprotein proteolytic cleavage product that is cleaved from NS12345 by the two-component proteinase NS2B-NS3 at the NS2B-NS3 site consisting of NS3, NS4A, NS4B, and NS5." [PMID:1433530, PRO:ES]
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modification
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 PR:000036828 |
   NS3
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   DenV-NS3
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  "A dengue virus genome polyprotein proteolytic cleavage product that is a non-structural, multifunctional protein encoded by the dengue virus RNA genome with a serine protease domain." [PMID:10744671, PRO:ES]
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|  Yes |
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organism-modification
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 PR:000044762 |
   NS3 (Dengue virus 2 Thailand/NGS-C/1944)
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   NS3 (DEN2N)
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  "An NS3 in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 1476-2093." [PRO:DNx]
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 Yes | 
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modification
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 PR:000036840 |
   NS4A-NS4B-NS5
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   DenV-NS4AB5
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  "A dengue virus genome polyprotein proteolytic cleavage product that is cleaved from NS345 by the two-component proteinase NS2B-NS3 at the NS3-NS4A site consisting of NS4A, 2K, NS4B, and NS5." [PMID:1531368, PRO:ES]
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modification
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 PR:000036841 |
   NS4AB
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   DenV-NS4AB
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  "A dengue virus genome polyprotein proteolytic cleavage product that is cleaved from NS4A-NS4B-NS5 by the two-component proteinase NS2B-NS3 at the NS4B-NS5 sites consisting of NS4A, 2K, and NS4B." [PMID:1531368, PRO:ES]
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modification
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 PR:000036830 |
   NS4A
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   DenV-NS4A
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  "A dengue virus genome polyprotein proteolytic cleavage product that is a highly hydrophobic non-structural protein encoded by the dengue virus RNA genome that associates with membranes via 4 internal hydrophobic regions which are all able to mediate membrane targeting of a cytosolic reporter protein." [PMID:17276984, PRO:ES]
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organism-modification
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 PR:000044763 |
   NS4A (Dengue virus 2 Thailand/NGS-C/1944)
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   NS4A (DEN2N)
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  "An NS4A in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2094-2220." [PRO:DNx]
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 Yes | 
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organism-modification
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 PR:000044764 |
   NS4A (Dengue virus 2 Thailand/16681/84)
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   NS4A (DEN26)
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  "An NS4A in Dengue virus 2 Thailand/16681/84. UniProtKB:P29990, 2094-2220." [PRO:DNx]
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 Yes | 
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modification
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 PR:000036842 |
   2KNS4B
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   DenV-2KNS4B
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  "A dengue virus genome polyprotein proteolytic cleavage product that assists in the processing of NS4AB consisting of 2K and NS4B." [PMID:21810535, PRO:ES]
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modification
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 PR:000036831 |
   2K
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   DenV-2K
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  "A dengue virus genome polyprotein proteolytic cleavage product that is the C-terminal region of NS4A serving as a signal sequence for the translocation of the adjacent NS4B into the endoplasmic reticulum (ER) lumen." [PMID:17276984, PRO:ES]
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organism-modification
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 PR:000044765 |
   2K (Dengue virus 2 Thailand/NGS-C/1944)
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   2K (DEN2N)
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  "A 2K in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2221-2243." [PRO:DNx]
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 Yes | 
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modification
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 PR:000036843 |
   NS4B-NS5
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   DenV-NS4B5
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  "A dengue virus genome polyprotein proteolytic cleavage product that is cleaved from NS4A-NS4B-NS5 at the NS4A-NS4B site consisting of NS4B and NS5, which is believed to be mediated by a host cell signal peptidase." [PMID:1531368, PRO:ES]
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modification
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 PR:000036873 |
   NS2B-NS3 polyprotein precursor
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   DenV-NS2B3
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  "A dengue virus genome polyprotein proteolytic cleavage product that is cleaved from NS12345 by the two-component protease NS2B-NS3 at the NS2A-NS2B and NS3-NS4 sites and consists of NS2B and NS3." [PMID:10744671, PRO:ES]
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modification
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 PR:000036998 |
   NS1-NS2A
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   DenV-NS12A
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  "A dengue virus genome polyprotein proteolytic cleavage product that is cleaved from NS12345 consisting of NS1 and NS2A. It includes two N-glycosylated residues at Asn-130 and Asn-207. Example: UniProtKB:P29990, 776-1345, Asn-905/Asn-982, MOD:00160." [PMID:15592895, PRO:DAN, PRO:ES]
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modification
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 PR:000036824 |
   NS1
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   DenV-NS1
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  "A dengue virus genome polyprotein proteolytic cleavage product that is the N-terminal most non-structural protein within the dengue virus genome polyprotein. Example: UniProtKB:P29990, 776-1127, Asn-905/Asn-982, MOD:00160." [PRO:ES]
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|  Yes |
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modification
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 PR:000037000 |
   NS1, with complex sugar attached
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   DenV-NS1/sugar(+)
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  "An NS1 that has had the glycan attached to the Asn-130 site modified to a complex sugar." [PRO:ES]
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|  Yes |
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modification
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 PR:000037001 |
   NS1, without complex sugar attached
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   DenV-NS1/sugar(-)
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  "An NS1 that has not had the glycan attached to the Asn-130 site modified to a complex sugar." [PRO:ES]
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|  Yes |
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organism-modification
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 PR:000044758 |
   NS1 (Dengue virus 2 Thailand/NGS-C/1944)
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   NS1 (DEN2N)
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  "An NS1 in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160." [PRO:DNx]
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 Yes | 
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modification
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 PR:000036825 |
   NS2A
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   DenV-NS2A
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  "A dengue virus genome polyprotein proteolytic cleavage product that is a non-structural protein encoded by the dengue virus RNA genome and a component of the viral replication complex." [PMID:23408612, PRO:ES]
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organism-modification
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 PR:000044759 |
   NS2A (Dengue virus 2 Thailand/NGS-C/1944)
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   NS2A (DEN2N)
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  "An NS2A in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 1128-1345." [PRO:DNx]
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 Yes | 
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organism-modification
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|
 PR:000044760 |
   NS2A (Dengue virus 2 Thailand/16681/84)
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   NS2A (DEN26)
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  "An NS2A in Dengue virus 2 Thailand/16681/84. UniProtKB:P29990, 1128-1345." [PRO:DNx]
 |
 Yes | 
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