Protein Ontology Report - mMYD88 PR:P22366 - http://purl.obolibrary.org/obo/PR_P22366

This page represents a class of proteins encompassing all the protein products of the Myd88 gene in Mus musculus.

Ontology Information
PRO ID	PR:P22366 Show OBO stanza / PAF / GPI
PRO name	myeloid differentiation primary response protein MyD88 (mouse)
Synonyms	PRO-short-label: EXACT: mMYD88 Gene-based: RELATED: Myd88
Definition	A myeloid differentiation primary response protein MyD88 that is encoded in the genome of mouse. [OMA:P22366, PRO:CNA]
PRO Category	organism-gene
Parent	PR:000001740 myeloid differentiation primary response protein MyD88
Gene Template	MGI:108005 Myd88
Taxon	NCBITaxon:10090 Mus musculus
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:P22366

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mMYD88 forms found in complexes

mMYD88 Component Complexes PR:000001740 MYD88 PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex PR:000001740 MYD88 PR:000025784 MYD88:TIRAP:activated TLR4 receptor PR:P22366-1 mMYD88/iso:1 PR:000027220 IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse) PR:P22366-1 mMYD88/iso:1 PR:000027187 IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse) PR:P22366-1 mMYD88/iso:1 PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse) PR:P22366-1 mMYD88/iso:1 PR:000027175 MYD88l:TIRAP:activated TLR4 receptor (mouse) PR:P22366-1 mMYD88/iso:1 PR:000027221 pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse) PR:P22366-1 mMYD88/iso:1 PR:000027267 IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse) PR:P22366-2 mMYD88/iso:2 PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:P22366-2 mMYD88/iso:2 acts_upstream_of_or_within GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665 PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse) acts_upstream_of_or_within GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665

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