|
|
 |
|
| | |
| | | | | | | | |
family
|
|
PR:000000046 |
TGF-beta
|
SKP1
|
"A TGF-beta-like cystine-knot cytokine whose propeptide region is a latent associated peptide (LAP) that remains associated to the mature TGF-beta after cleavage and secretion, keeping TGF-beta inactive. TGF-beta is the founding member of the cystine-knot cytokine family, and is related to the activin/inhibin, anti-Muellerian hormone, and bone morphogenic protein families, which are all involved in the regulation of cell growth and differentiation." [PIRSF:PIRSF001787]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000182 |
TGF-beta 1
|
TGFB1
|
"A TGF-beta that is a translation product of the human TGFB1 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P01137 |
transforming growth factor beta-1 (human)
|
hTGFB1
|
"A TGF-beta 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01137]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:000000398 |
TGF-beta 1 sequence variant L10P (human)
|
hTGFB1/var:L10P
|
"A transforming growth factor beta-1 (human) that has a Pro residue at the position equivalent to Leu-10 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Leu-10, CHEBI:50342." [PMID:12202987, PMID:3861940, PMID:9783545, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:000000399 |
TGF-beta 1 sequence variant T81H (human)
|
hTGFB1/var:T81H
|
"A transforming growth factor beta-1 (human) that has a His residue at the position equivalent to Tyr-81 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Tyr-81, CHEBI:29979." [PMID:11062463, PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021903 |
TGF-beta 1 sequence variant T81H, signal peptide removed form (human)
|
hTGFB1/var:T81H/SigPep-
|
"A TGF-beta 1 sequence variant T81H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Tyr-81, CHEBI:29979." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000619 |
TGF-beta 1 sequence variant T81H cleaved 1 (human)
|
hTGFB1/var:T81H/Clv:1
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000620 |
TGF-beta 1 sequence variant T81H cleaved 2 (human)
|
hTGFB1/var:T81H/Clv:2
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:000000400 |
TGF-beta 1 sequence variant R218C (human)
|
hTGFB1/var:R218C
|
"A transforming growth factor beta-1 (human) that has a Cys residue at the position equivalent to Arg-218 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Arg-218, CHEBI:29950." [PMID:10973241, PMID:11062463, PMID:12493741, PMID:12843182, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021904 |
TGF-beta 1 sequence variant R218C, signal peptide removed form (human)
|
hTGFB1/var:R218C/SigPep-
|
"A TGF-beta 1 sequence variant R218C (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29950." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000621 |
TGF-beta 1 sequence variant R218C cleaved 1 (human)
|
hTGFB1/var:R218C/Clv:1
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000622 |
TGF-beta 1 sequence variant R218C cleaved 2 (human)
|
hTGFB1/var:R218C/Clv:2
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide (PR:000000621). UniProtKB:P01137, 30-278, Arg-218, CHEBI:29950." [PMID:10973241, PMID:11062463, PMID:11278244, PMID:12493741, PMID:12843182, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:000000401 |
TGF-beta 1 sequence variant R218H (human)
|
hTGFB1/var:R218H
|
"A transforming growth factor beta-1 (human) that has a His residue at the position equivalent to Arg-218 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Arg-218, CHEBI:29979." [PMID:11062463, PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021907 |
TGF-beta 1 sequence variant R218H, signal peptide removed form (human)
|
hTGFB1/var:R218H/SigPep-
|
"A TGF-beta 1 sequence variant R218H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29979." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000627 |
TGF-beta 1 sequence variant R218H cleaved 1 (human)
|
hTGFB1/var:R218H/Clv:1
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000628 |
TGF-beta 1 sequence variant R218H cleaved 2 (human)
|
hTGFB1/var:R218H/Clv:2
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide. UniProtKB:P01137, 30-278, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:000000402 |
TGF-beta 1 sequence variant H222D (human)
|
hTGFB1/var:H222D
|
"A transforming growth factor beta-1 (human) that has an Asp residue at the position equivalent to His-222 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, His-222, CHEBI:29958." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021905 |
TGF-beta 1 sequence variant H222D, signal peptide removed form (human)
|
hTGFB1/var:H222D/SigPep-
|
"A TGF-beta 1 sequence variant H222D (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, His-222, CHEBI:29958." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000623 |
TGF-beta 1 sequence variant H222D cleaved 1 (human)
|
hTGFB1/var:H222D/Clv:1
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, His-222, CHEBI:29958." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000624 |
TGF-beta 1 sequence variant H222D cleaved 2 (human)
|
hTGFB1/var:H222D/Clv:2
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, His-222, CHEBI:29958." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:000000403 |
TGF-beta 1 sequence variant C225R (human)
|
hTGFB1/var:C225R
|
"A transforming growth factor beta-1 (human) that has an Arg residue at the position equivalent to Cys-225 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Cys-225, CHEBI:29952." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021906 |
TGF-beta 1 sequence variant C225R, signal peptide removed form (human)
|
hTGFB1/var:C225R/SigPep-
|
"A TGF-beta 1 sequence variant C225R (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Cys-225, CHEBI:29952." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000625 |
TGF-beta 1 sequence variant C225R cleaved 1 (human)
|
hTGFB1/var:C225R/Clv:1
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000626 |
TGF-beta 1 sequence variant C225R cleaved 2 (human)
|
hTGFB1/var:C225R/Clv:2
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P01137-1 |
transforming growth factor beta-1 isoform 1 (human)
|
hTGFB1/iso:1
|
"A TGF-beta 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025927 |
TGF-beta 1 isoform 1 mature form (human)
|
hTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in human. UniProtKB:P01137-1, 279-390." [PMID:3162913]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026335 |
TGF-beta 1 isoform 1 inactive form (human)
|
hTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000049430 |
transforming growth factor beta-1, signal peptide removed form (human)
|
hTGFB1/SigPep-
|
"A transforming growth factor beta-1 (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390." [PRO:DNx, Reactome:R-HSA-114705]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021903 |
TGF-beta 1 sequence variant T81H, signal peptide removed form (human)
|
hTGFB1/var:T81H/SigPep-
|
"A TGF-beta 1 sequence variant T81H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Tyr-81, CHEBI:29979." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000619 |
TGF-beta 1 sequence variant T81H cleaved 1 (human)
|
hTGFB1/var:T81H/Clv:1
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000620 |
TGF-beta 1 sequence variant T81H cleaved 2 (human)
|
hTGFB1/var:T81H/Clv:2
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021904 |
TGF-beta 1 sequence variant R218C, signal peptide removed form (human)
|
hTGFB1/var:R218C/SigPep-
|
"A TGF-beta 1 sequence variant R218C (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29950." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000621 |
TGF-beta 1 sequence variant R218C cleaved 1 (human)
|
hTGFB1/var:R218C/Clv:1
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000622 |
TGF-beta 1 sequence variant R218C cleaved 2 (human)
|
hTGFB1/var:R218C/Clv:2
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide (PR:000000621). UniProtKB:P01137, 30-278, Arg-218, CHEBI:29950." [PMID:10973241, PMID:11062463, PMID:11278244, PMID:12493741, PMID:12843182, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021905 |
TGF-beta 1 sequence variant H222D, signal peptide removed form (human)
|
hTGFB1/var:H222D/SigPep-
|
"A TGF-beta 1 sequence variant H222D (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, His-222, CHEBI:29958." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000623 |
TGF-beta 1 sequence variant H222D cleaved 1 (human)
|
hTGFB1/var:H222D/Clv:1
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, His-222, CHEBI:29958." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000624 |
TGF-beta 1 sequence variant H222D cleaved 2 (human)
|
hTGFB1/var:H222D/Clv:2
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, His-222, CHEBI:29958." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021906 |
TGF-beta 1 sequence variant C225R, signal peptide removed form (human)
|
hTGFB1/var:C225R/SigPep-
|
"A TGF-beta 1 sequence variant C225R (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Cys-225, CHEBI:29952." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000625 |
TGF-beta 1 sequence variant C225R cleaved 1 (human)
|
hTGFB1/var:C225R/Clv:1
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000626 |
TGF-beta 1 sequence variant C225R cleaved 2 (human)
|
hTGFB1/var:C225R/Clv:2
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021907 |
TGF-beta 1 sequence variant R218H, signal peptide removed form (human)
|
hTGFB1/var:R218H/SigPep-
|
"A TGF-beta 1 sequence variant R218H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29979." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000627 |
TGF-beta 1 sequence variant R218H cleaved 1 (human)
|
hTGFB1/var:R218H/Clv:1
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000628 |
TGF-beta 1 sequence variant R218H cleaved 2 (human)
|
hTGFB1/var:R218H/Clv:2
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide. UniProtKB:P01137, 30-278, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026335 |
TGF-beta 1 isoform 1 inactive form (human)
|
hTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000066327 |
transforming growth factor beta-1 deaminated 1 (human)
|
hTGFB1/Deam:1
|
"A transforming growth factor beta-1 (human) that has been deaminated on the residue at the position equivalent to Asn-176 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Asn-176, MOD:00684." [IEDB_epitope:2000821, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000069562 |
transforming growth factor beta-1 cysteinylated 1 (human)
|
hTGFB1/Cyst:1
|
"A transforming growth factor beta-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-387 of the amino acid sequence represented by UniProtKB:P01137. UniProtKB:P01137, Cys-387, MOD:00765." [IEDB_epitope:2123229, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P04202 |
transforming growth factor beta-1 proprotein (mouse)
|
mTGFB1
|
"A TGF-beta 1 that is encoded in the genome of mouse." [OMA:P04202, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P04202-1 |
transforming growth factor beta-1 isoform 1 (mouse)
|
mTGFB1/iso:1
|
"A TGF-beta 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025928 |
TGF-beta 1 isoform 1 mature form (mouse)
|
mTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in mouse. UniProtKB:P04202-1, 279-390." [PMID:2209468]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036529 |
TGF-beta 1 isoform 1 inactive form (mouse)
|
mTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P04202-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1821856, PMID:9008713, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P09533 |
transforming growth factor beta-1 (green monkey)
|
GrMonkey-TGFB1
|
"A TGF-beta 1 that is encoded in the genome of green monkey." [PRO:DAN, UniProtKB:P09533]
|
|
|
|
|
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| | | | | | | | |
| | |
organism-sequence
|
|
PR:P09533-1 |
transforming growth factor beta-1 isoform 1 (green monkey)
|
GrMonkey-TGFB1/iso:1
|
"A TGF-beta 1 isoform 1 that is encoded in the genome of green monkey." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025930 |
TGF-beta 1 isoform 1 mature form (green monkey)
|
GrMonkey-TGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in green monkey. UniProtKB:P09533-1, 279-390." [PMID:3185545]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036527 |
TGF-beta 1 isoform 1 inactive form (green monkey)
|
GrMonkey-TGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in green monkey, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1448117, PMID:2677679, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P17246 |
transforming growth factor beta-1 (rat)
|
rTGFB1
|
"A TGF-beta 1 that is encoded in the genome of rat." [OMA:P17246, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000025929 |
TGF-beta 1 isoform 1 mature form (rat)
|
rTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in rat. UniProtKB:P17246-1, 279-390." [PMID:11453552]
|
Yes |
Yes |
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q9VQG9 |
dawdle, isoform A (fruit fly)
|
fly-TGFB1
|
"A TGF-beta 1 that is encoded in the genome of fruit fly." [OMA:Q9VQG9, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000397 |
TGF-beta 1 isoform 1
|
TGFB1/iso:1
|
"A TGF-beta 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01137-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P01137-1 |
transforming growth factor beta-1 isoform 1 (human)
|
hTGFB1/iso:1
|
"A TGF-beta 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025927 |
TGF-beta 1 isoform 1 mature form (human)
|
hTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in human. UniProtKB:P01137-1, 279-390." [PMID:3162913]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026335 |
TGF-beta 1 isoform 1 inactive form (human)
|
hTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P04202-1 |
transforming growth factor beta-1 isoform 1 (mouse)
|
mTGFB1/iso:1
|
"A TGF-beta 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025928 |
TGF-beta 1 isoform 1 mature form (mouse)
|
mTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in mouse. UniProtKB:P04202-1, 279-390." [PMID:2209468]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036529 |
TGF-beta 1 isoform 1 inactive form (mouse)
|
mTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P04202-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1821856, PMID:9008713, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P09533-1 |
transforming growth factor beta-1 isoform 1 (green monkey)
|
GrMonkey-TGFB1/iso:1
|
"A TGF-beta 1 isoform 1 that is encoded in the genome of green monkey." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025930 |
TGF-beta 1 isoform 1 mature form (green monkey)
|
GrMonkey-TGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in green monkey. UniProtKB:P09533-1, 279-390." [PMID:3185545]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036527 |
TGF-beta 1 isoform 1 inactive form (green monkey)
|
GrMonkey-TGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in green monkey, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1448117, PMID:2677679, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000616 |
TGF-beta 1 isoform 1 mature form
|
TGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature protein. Example: UniProtKB:P01137-1, 279-390." [PMID:3162913, PRO:CNA, PRO:DAN]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025927 |
TGF-beta 1 isoform 1 mature form (human)
|
hTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in human. UniProtKB:P01137-1, 279-390." [PMID:3162913]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025928 |
TGF-beta 1 isoform 1 mature form (mouse)
|
mTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in mouse. UniProtKB:P04202-1, 279-390." [PMID:2209468]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025929 |
TGF-beta 1 isoform 1 mature form (rat)
|
rTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in rat. UniProtKB:P17246-1, 279-390." [PMID:11453552]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025930 |
TGF-beta 1 isoform 1 mature form (green monkey)
|
GrMonkey-TGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in green monkey. UniProtKB:P09533-1, 279-390." [PMID:3185545]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000002555 |
TGF-beta 1 isoform 1 unmodified form
|
TGFB1/iso:1/UnMod
|
"A TGF-beta 1 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000025454 |
TGF-beta 1 isoform 1, signal peptide removed form
|
TGFB1/iso:1/SigPep-
|
"A TGF-beta 1 isoform 1 that has had the signal peptide removed." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000617 |
TGF-beta 1 isoform 1 latency associated peptide
|
TGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1, signal peptide removed form that has had the C-terminal mature peptide removed and has been N-glycosylated mainly at either one of the two first consensus N-glycosylation sites. Example: UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:3162913, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000618 |
TGF-beta 1 isoform 1 inactive form
|
TGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1, signal peptide removed form that has been cleaved at the dibasic cleavage site, rendering the latency associated peptide (LAP) and the mature protein non-covalently bound. This form is glycosylated mainly at either one or the two first consensus glycosylation sites within the LAP sequence. Example: UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:3162913, PMID:3185545, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000026335 |
TGF-beta 1 isoform 1 inactive form (human)
|
hTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036527 |
TGF-beta 1 isoform 1 inactive form (green monkey)
|
GrMonkey-TGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in green monkey, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1448117, PMID:2677679, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036529 |
TGF-beta 1 isoform 1 inactive form (mouse)
|
mTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P04202-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1821856, PMID:9008713, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000018291 |
TGF-beta 1, signal peptide removed form
|
TGFB1/SigPep-
|
"A TGF-beta 1 that has had the signal peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000025454 |
TGF-beta 1 isoform 1, signal peptide removed form
|
TGFB1/iso:1/SigPep-
|
"A TGF-beta 1 isoform 1 that has had the signal peptide removed." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000617 |
TGF-beta 1 isoform 1 latency associated peptide
|
TGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1, signal peptide removed form that has had the C-terminal mature peptide removed and has been N-glycosylated mainly at either one of the two first consensus N-glycosylation sites. Example: UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:3162913, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000618 |
TGF-beta 1 isoform 1 inactive form
|
TGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1, signal peptide removed form that has been cleaved at the dibasic cleavage site, rendering the latency associated peptide (LAP) and the mature protein non-covalently bound. This form is glycosylated mainly at either one or the two first consensus glycosylation sites within the LAP sequence. Example: UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:3162913, PMID:3185545, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000026335 |
TGF-beta 1 isoform 1 inactive form (human)
|
hTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036527 |
TGF-beta 1 isoform 1 inactive form (green monkey)
|
GrMonkey-TGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in green monkey, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P09533-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1448117, PMID:2677679, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036529 |
TGF-beta 1 isoform 1 inactive form (mouse)
|
mTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P04202-1, 30-278, 279-390, Asn-82, MOD:00160." [PMID:1821856, PMID:9008713, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000049430 |
transforming growth factor beta-1, signal peptide removed form (human)
|
hTGFB1/SigPep-
|
"A transforming growth factor beta-1 (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390." [PRO:DNx, Reactome:R-HSA-114705]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021903 |
TGF-beta 1 sequence variant T81H, signal peptide removed form (human)
|
hTGFB1/var:T81H/SigPep-
|
"A TGF-beta 1 sequence variant T81H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Tyr-81, CHEBI:29979." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000619 |
TGF-beta 1 sequence variant T81H cleaved 1 (human)
|
hTGFB1/var:T81H/Clv:1
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000620 |
TGF-beta 1 sequence variant T81H cleaved 2 (human)
|
hTGFB1/var:T81H/Clv:2
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021904 |
TGF-beta 1 sequence variant R218C, signal peptide removed form (human)
|
hTGFB1/var:R218C/SigPep-
|
"A TGF-beta 1 sequence variant R218C (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29950." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000621 |
TGF-beta 1 sequence variant R218C cleaved 1 (human)
|
hTGFB1/var:R218C/Clv:1
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000622 |
TGF-beta 1 sequence variant R218C cleaved 2 (human)
|
hTGFB1/var:R218C/Clv:2
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide (PR:000000621). UniProtKB:P01137, 30-278, Arg-218, CHEBI:29950." [PMID:10973241, PMID:11062463, PMID:11278244, PMID:12493741, PMID:12843182, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021905 |
TGF-beta 1 sequence variant H222D, signal peptide removed form (human)
|
hTGFB1/var:H222D/SigPep-
|
"A TGF-beta 1 sequence variant H222D (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, His-222, CHEBI:29958." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000623 |
TGF-beta 1 sequence variant H222D cleaved 1 (human)
|
hTGFB1/var:H222D/Clv:1
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, His-222, CHEBI:29958." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000624 |
TGF-beta 1 sequence variant H222D cleaved 2 (human)
|
hTGFB1/var:H222D/Clv:2
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, His-222, CHEBI:29958." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021906 |
TGF-beta 1 sequence variant C225R, signal peptide removed form (human)
|
hTGFB1/var:C225R/SigPep-
|
"A TGF-beta 1 sequence variant C225R (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Cys-225, CHEBI:29952." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000625 |
TGF-beta 1 sequence variant C225R cleaved 1 (human)
|
hTGFB1/var:C225R/Clv:1
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000626 |
TGF-beta 1 sequence variant C225R cleaved 2 (human)
|
hTGFB1/var:C225R/Clv:2
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000021907 |
TGF-beta 1 sequence variant R218H, signal peptide removed form (human)
|
hTGFB1/var:R218H/SigPep-
|
"A TGF-beta 1 sequence variant R218H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29979." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000627 |
TGF-beta 1 sequence variant R218H cleaved 1 (human)
|
hTGFB1/var:R218H/Clv:1
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000000628 |
TGF-beta 1 sequence variant R218H cleaved 2 (human)
|
hTGFB1/var:R218H/Clv:2
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide. UniProtKB:P01137, 30-278, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000026335 |
TGF-beta 1 isoform 1 inactive form (human)
|
hTGFB1/iso:1/inactive
|
"A TGF-beta 1 isoform 1 inactive form in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P01137-1, 30-278, 279-390, Asn-82, MOD:00160." [PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000018292 |
TGF-beta 1 proteolytic cleavage product
|
TGFB1/ClvPrd
|
"A TGF-beta 1 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000616 |
TGF-beta 1 isoform 1 mature form
|
TGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature protein. Example: UniProtKB:P01137-1, 279-390." [PMID:3162913, PRO:CNA, PRO:DAN]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025927 |
TGF-beta 1 isoform 1 mature form (human)
|
hTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in human. UniProtKB:P01137-1, 279-390." [PMID:3162913]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025928 |
TGF-beta 1 isoform 1 mature form (mouse)
|
mTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in mouse. UniProtKB:P04202-1, 279-390." [PMID:2209468]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025929 |
TGF-beta 1 isoform 1 mature form (rat)
|
rTGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in rat. UniProtKB:P17246-1, 279-390." [PMID:11453552]
|
Yes |
Yes |
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000025930 |
TGF-beta 1 isoform 1 mature form (green monkey)
|
GrMonkey-TGFB1/iso:1/mature
|
"A TGF-beta 1 isoform 1 mature form in green monkey. UniProtKB:P09533-1, 279-390." [PMID:3185545]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000617 |
TGF-beta 1 isoform 1 latency associated peptide
|
TGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1, signal peptide removed form that has had the C-terminal mature peptide removed and has been N-glycosylated mainly at either one of the two first consensus N-glycosylation sites. Example: UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:3162913, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036526 |
TGF-beta 1 isoform 1 latency associated peptide (human)
|
hTGFB1/iso:1/LAP
|
"A TGF-beta 1 isoform 1 latency associated peptide in human. UniProtKB:P01137-1, 30-279, Asn-82, MOD:00160." [PMID:17015622, PMID:3162913, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000619 |
TGF-beta 1 sequence variant T81H cleaved 1 (human)
|
hTGFB1/var:T81H/Clv:1
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000620 |
TGF-beta 1 sequence variant T81H cleaved 2 (human)
|
hTGFB1/var:T81H/Clv:2
|
"A TGF-beta 1 sequence variant T81H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Tyr-81, CHEBI:29979." [PMID:12493741, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000621 |
TGF-beta 1 sequence variant R218C cleaved 1 (human)
|
hTGFB1/var:R218C/Clv:1
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000622 |
TGF-beta 1 sequence variant R218C cleaved 2 (human)
|
hTGFB1/var:R218C/Clv:2
|
"A TGF-beta 1 sequence variant R218C, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide (PR:000000621). UniProtKB:P01137, 30-278, Arg-218, CHEBI:29950." [PMID:10973241, PMID:11062463, PMID:11278244, PMID:12493741, PMID:12843182, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000623 |
TGF-beta 1 sequence variant H222D cleaved 1 (human)
|
hTGFB1/var:H222D/Clv:1
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, His-222, CHEBI:29958." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000624 |
TGF-beta 1 sequence variant H222D cleaved 2 (human)
|
hTGFB1/var:H222D/Clv:2
|
"A TGF-beta 1 sequence variant H222D, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, His-222, CHEBI:29958." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000625 |
TGF-beta 1 sequence variant C225R cleaved 1 (human)
|
hTGFB1/var:C225R/Clv:1
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Cys-225, CHEBI:29952." [PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000626 |
TGF-beta 1 sequence variant C225R cleaved 2 (human)
|
hTGFB1/var:C225R/Clv:2
|
"A TGF-beta 1 sequence variant C225R, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). UniProtKB:P01137, 30-278, Cys-225, CHEBI:29952." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000627 |
TGF-beta 1 sequence variant R218H cleaved 1 (human)
|
hTGFB1/var:R218H/Clv:1
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the latency associated peptide (LAP). UniProtKB:P01137, 279-390, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000000628 |
TGF-beta 1 sequence variant R218H cleaved 2 (human)
|
hTGFB1/var:R218H/Clv:2
|
"A TGF-beta 1 sequence variant R218H, signal peptide removed form (human) that has been processed by subsequent removal of the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP). This form has decreased affinity for the mature peptide. UniProtKB:P01137, 30-278, Arg-218, CHEBI:29979." [PMID:11278244, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000183 |
TGF-beta 2
|
TGFB2
|
"A TGF-beta that is a translation product of the human TGFB2 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P27090 |
transforming growth factor beta-2 proprotein (mouse)
|
mTGFB2
|
"A TGF-beta 2 that is encoded in the genome of mouse." [OMA:P27090, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P27090-1 |
transforming growth factor beta-2 isoform 1 (mouse)
|
mTGFB2/iso:A
|
"A TGF-beta 2 isoform A that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036531 |
TGF-beta 2 isoform A cleaved 2 (mouse)
|
mTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in mouse. UniProtKB:P27090-1, 20-302." [PMID:14985127, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P61812 |
transforming growth factor beta-2 (human)
|
hTGFB2
|
"A TGF-beta 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P61812]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P61812-1 |
transforming growth factor beta-2 isoform A (human)
|
hTGFB2/iso:A
|
"A TGF-beta 2 isoform A that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036530 |
TGF-beta 2 isoform A cleaved 1 (human)
|
hTGFB2/iso:A/Clv:1
|
"A TGF-beta 2 isoform A cleaved 1 in human. UniProtKB:P61812-1, 303-414." [PMID:15944186, PMID:16227582, PMID:2119582, PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036532 |
TGF-beta 2 isoform A cleaved 2 (human)
|
hTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in human. UniProtKB:P61812-1, 20-302." [PMID:3162913, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036533 |
TGF-beta 2 isoform A cleaved 3 (human)
|
hTGFB2/iso:A/Clv:3
|
"A TGF-beta 2 isoform A cleaved 3 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-1, 20-302, 303-414." [PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P61812-2 |
transforming growth factor beta-2 isoform B (human)
|
hTGFB2/iso:B
|
"A TGF-beta 2 isoform B that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036534 |
TGF-beta 2 isoform B cleaved 1 (human)
|
hTGFB2/iso:B/Clv:1
|
"A TGF-beta 2 isoform B cleaved 1 in human. UniProtKB:P61812-2, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036535 |
TGF-beta 2 isoform B cleaved 2 (human)
|
hTGFB2/iso:B/Clv:2
|
"A TGF-beta 2 isoform B cleaved 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-2, 20-330, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-modification
|
|
PR:000069517 |
transforming growth factor beta-2 methylated 1 (human)
|
hTGFB2/Me:1
|
"A transforming growth factor beta-2 (human) that has been methylated on the residue at the position equivalent to Cys-4 of the amino acid sequence represented by UniProtKB:P61812. UniProtKB:P61812, Cys-4, MOD:00660." [IEDB_epitope:1019772, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q07257 |
transforming growth factor beta-2 proprotein (rat)
|
rTGFB2
|
"A TGF-beta 2 that is encoded in the genome of rat." [OMA:Q07257, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q07257-1 |
transforming growth factor beta-2 proprotein isoform rTGF-beta2B (rat)
|
rTGFB2/iso:rTGF-beta2B
|
"A transforming growth factor beta-2 proprotein (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07257-1." [PRO:DNx, UniProtKB:Q07257]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q07257-2 |
transforming growth factor beta-2 isoform A (rat)
|
rTGFB2/iso:A
|
"A TGF-beta 2 isoform A that is encoded in the genome of rat." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000404 |
TGF-beta 2 isoform A
|
TGFB2/iso:A
|
"A TGF-beta 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61812-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P27090-1 |
transforming growth factor beta-2 isoform 1 (mouse)
|
mTGFB2/iso:A
|
"A TGF-beta 2 isoform A that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036531 |
TGF-beta 2 isoform A cleaved 2 (mouse)
|
mTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in mouse. UniProtKB:P27090-1, 20-302." [PMID:14985127, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P61812-1 |
transforming growth factor beta-2 isoform A (human)
|
hTGFB2/iso:A
|
"A TGF-beta 2 isoform A that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036530 |
TGF-beta 2 isoform A cleaved 1 (human)
|
hTGFB2/iso:A/Clv:1
|
"A TGF-beta 2 isoform A cleaved 1 in human. UniProtKB:P61812-1, 303-414." [PMID:15944186, PMID:16227582, PMID:2119582, PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036532 |
TGF-beta 2 isoform A cleaved 2 (human)
|
hTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in human. UniProtKB:P61812-1, 20-302." [PMID:3162913, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036533 |
TGF-beta 2 isoform A cleaved 3 (human)
|
hTGFB2/iso:A/Clv:3
|
"A TGF-beta 2 isoform A cleaved 3 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-1, 20-302, 303-414." [PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:Q07257-2 |
transforming growth factor beta-2 isoform A (rat)
|
rTGFB2/iso:A
|
"A TGF-beta 2 isoform A that is encoded in the genome of rat." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000629 |
TGF-beta 2 isoform A cleaved 1
|
TGFB2/iso:A/Clv:1
|
"A TGF-beta 2 isoform A that has been processed by proteolytic cleavage and released from the latent complex. This form, cross-linked to an identical chain, is the active mature protein." [PMID:3476488]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036530 |
TGF-beta 2 isoform A cleaved 1 (human)
|
hTGFB2/iso:A/Clv:1
|
"A TGF-beta 2 isoform A cleaved 1 in human. UniProtKB:P61812-1, 303-414." [PMID:15944186, PMID:16227582, PMID:2119582, PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000021908 |
TGF-beta 2 isoform A, signal peptide removed form
|
TGFB2/iso:A/SigPep-
|
"A TGF-beta 2 isoform A that has had the signal peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000630 |
TGF-beta 2 isoform A cleaved 2
|
TGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A, signal peptide removed form that has been processed by subsequent removal of the C-terminal mature protein. This chain is referred as to the latency associated peptide (LAP)." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036531 |
TGF-beta 2 isoform A cleaved 2 (mouse)
|
mTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in mouse. UniProtKB:P27090-1, 20-302." [PMID:14985127, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036532 |
TGF-beta 2 isoform A cleaved 2 (human)
|
hTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in human. UniProtKB:P61812-1, 20-302." [PMID:3162913, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000631 |
TGF-beta 2 isoform A cleaved 3
|
TGFB2/iso:A/Clv:3
|
"A TGF-beta 2 isoform A, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PMID:10224129]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036533 |
TGF-beta 2 isoform A cleaved 3 (human)
|
hTGFB2/iso:A/Clv:3
|
"A TGF-beta 2 isoform A cleaved 3 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-1, 20-302, 303-414." [PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000405 |
TGF-beta 2 isoform B
|
TGFB2/iso:B
|
"A TGF-beta 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61812-2 or a 1:1 ortholog thereof." [PMID:16868931, PMID:1777240, PMID:2850146, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P61812-2 |
transforming growth factor beta-2 isoform B (human)
|
hTGFB2/iso:B
|
"A TGF-beta 2 isoform B that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036534 |
TGF-beta 2 isoform B cleaved 1 (human)
|
hTGFB2/iso:B/Clv:1
|
"A TGF-beta 2 isoform B cleaved 1 in human. UniProtKB:P61812-2, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036535 |
TGF-beta 2 isoform B cleaved 2 (human)
|
hTGFB2/iso:B/Clv:2
|
"A TGF-beta 2 isoform B cleaved 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-2, 20-330, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000632 |
TGF-beta 2 isoform B cleaved 1
|
TGFB2/iso:B/Clv:1
|
"A TGF-beta 2 isoform B that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature peptide." [PMID:1777240]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036534 |
TGF-beta 2 isoform B cleaved 1 (human)
|
hTGFB2/iso:B/Clv:1
|
"A TGF-beta 2 isoform B cleaved 1 in human. UniProtKB:P61812-2, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000021909 |
TGF-beta 2 isoform B, signal peptide removed form
|
TGFB2/iso:B/SigPep-
|
"A TGF-beta 2 isoform B that has had the signal peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000633 |
TGF-beta 2 isoform B cleaved 2
|
TGFB2/iso:B/Clv:2
|
"A TGF-beta 2 isoform B, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PMID:1777240]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036535 |
TGF-beta 2 isoform B cleaved 2 (human)
|
hTGFB2/iso:B/Clv:2
|
"A TGF-beta 2 isoform B cleaved 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-2, 20-330, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000018293 |
TGF-beta 2 proteolytic cleavage product
|
TGFB2/ClvPrd
|
"A TGF-beta 2 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000629 |
TGF-beta 2 isoform A cleaved 1
|
TGFB2/iso:A/Clv:1
|
"A TGF-beta 2 isoform A that has been processed by proteolytic cleavage and released from the latent complex. This form, cross-linked to an identical chain, is the active mature protein." [PMID:3476488]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036530 |
TGF-beta 2 isoform A cleaved 1 (human)
|
hTGFB2/iso:A/Clv:1
|
"A TGF-beta 2 isoform A cleaved 1 in human. UniProtKB:P61812-1, 303-414." [PMID:15944186, PMID:16227582, PMID:2119582, PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000630 |
TGF-beta 2 isoform A cleaved 2
|
TGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A, signal peptide removed form that has been processed by subsequent removal of the C-terminal mature protein. This chain is referred as to the latency associated peptide (LAP)." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036531 |
TGF-beta 2 isoform A cleaved 2 (mouse)
|
mTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in mouse. UniProtKB:P27090-1, 20-302." [PMID:14985127, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036532 |
TGF-beta 2 isoform A cleaved 2 (human)
|
hTGFB2/iso:A/Clv:2
|
"A TGF-beta 2 isoform A cleaved 2 in human. UniProtKB:P61812-1, 20-302." [PMID:3162913, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000631 |
TGF-beta 2 isoform A cleaved 3
|
TGFB2/iso:A/Clv:3
|
"A TGF-beta 2 isoform A, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PMID:10224129]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036533 |
TGF-beta 2 isoform A cleaved 3 (human)
|
hTGFB2/iso:A/Clv:3
|
"A TGF-beta 2 isoform A cleaved 3 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-1, 20-302, 303-414." [PMID:3162913, PMID:3476488, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000632 |
TGF-beta 2 isoform B cleaved 1
|
TGFB2/iso:B/Clv:1
|
"A TGF-beta 2 isoform B that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature peptide." [PMID:1777240]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036534 |
TGF-beta 2 isoform B cleaved 1 (human)
|
hTGFB2/iso:B/Clv:1
|
"A TGF-beta 2 isoform B cleaved 1 in human. UniProtKB:P61812-2, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000633 |
TGF-beta 2 isoform B cleaved 2
|
TGFB2/iso:B/Clv:2
|
"A TGF-beta 2 isoform B, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PMID:1777240]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036535 |
TGF-beta 2 isoform B cleaved 2 (human)
|
hTGFB2/iso:B/Clv:2
|
"A TGF-beta 2 isoform B cleaved 2 in human, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P61812-2, 20-330, 331-442." [PMID:1777240, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | | |
gene
|
|
PR:000000184 |
TGF-beta 3
|
TGFB3
|
"A TGF-beta that is a translation product of the human TGFB3 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P10600 |
transforming growth factor beta-3 (human)
|
hTGFB3
|
"A TGF-beta 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P10600]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P10600-1 |
transforming growth factor beta-3 isoform 1 (human)
|
hTGFB3/iso:1
|
"A TGF-beta 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036536 |
TGF-beta 3 isoform 1 cleaved 1 (human)
|
hTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in human. UniProtKB:P10600-1, 301-412." [PMID:18243111, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P10600-2 |
transforming growth factor beta-3 isoform h2 (human)
|
hTGFB3/iso:h2
|
"A transforming growth factor beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10600-2." [PRO:DNx, UniProtKB:P10600]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P16047 |
transforming growth factor beta-3 proprotein (chicken)
|
chick-TGFB3
|
"A TGF-beta 3 that is encoded in the genome of chicken." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:P17125 |
transforming growth factor beta-3 (mouse)
|
mTGFB3
|
"A TGF-beta 3 that is encoded in the genome of mouse." [OMA:P17125, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P17125-1 |
transforming growth factor beta-3 isoform 1 (mouse)
|
mTGFB3/iso:1
|
"A TGF-beta 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036537 |
TGF-beta 3 isoform 1 cleaved 1 (mouse)
|
mTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in mouse. UniProtKB:P17125-1, 299-410." [PMID:1821856, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036538 |
TGF-beta 3 isoform 1 cleaved 3 (mouse)
|
mTGFB3/iso:1/Clv:3
|
"A TGF-beta 3 isoform 1 cleaved 3 in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P17125-1, 30-298, 299-410." [PMID:1821856, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
organism-gene
|
|
PR:Q07258 |
transforming growth factor beta-3 proprotein (rat)
|
rTGFB3
|
"A TGF-beta 3 that is encoded in the genome of rat." [OMA:Q07258, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | | |
sequence
|
|
PR:000000406 |
TGF-beta 3 isoform 1
|
TGFB3/iso:1
|
"A TGF-beta 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10600-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P10600-1 |
transforming growth factor beta-3 isoform 1 (human)
|
hTGFB3/iso:1
|
"A TGF-beta 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036536 |
TGF-beta 3 isoform 1 cleaved 1 (human)
|
hTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in human. UniProtKB:P10600-1, 301-412." [PMID:18243111, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
organism-sequence
|
|
PR:P17125-1 |
transforming growth factor beta-3 isoform 1 (mouse)
|
mTGFB3/iso:1
|
"A TGF-beta 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036537 |
TGF-beta 3 isoform 1 cleaved 1 (mouse)
|
mTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in mouse. UniProtKB:P17125-1, 299-410." [PMID:1821856, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036538 |
TGF-beta 3 isoform 1 cleaved 3 (mouse)
|
mTGFB3/iso:1/Clv:3
|
"A TGF-beta 3 isoform 1 cleaved 3 in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P17125-1, 30-298, 299-410." [PMID:1821856, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000634 |
TGF-beta 3 isoform 1 cleaved 1
|
TGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature peptide." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036536 |
TGF-beta 3 isoform 1 cleaved 1 (human)
|
hTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in human. UniProtKB:P10600-1, 301-412." [PMID:18243111, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036537 |
TGF-beta 3 isoform 1 cleaved 1 (mouse)
|
mTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in mouse. UniProtKB:P17125-1, 299-410." [PMID:1821856, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000021910 |
TGF-beta 3 isoform 1, signal peptide removed form
|
TGFB3/iso:1/SigPep-
|
"A TGF-beta 3 isoform 1 that has had the signal peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000635 |
TGF-beta 3 isoform 1 cleaved 2
|
TGFB3/iso:1/Clv:2
|
"A TGF-beta 3 isoform 1, signal peptide removed form that has been processed by proteolytic cleavage to remove the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP)." [PMID:11821050]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
modification
|
|
PR:000000636 |
TGF-beta 3 isoform 1 cleaved 3
|
TGFB3/iso:1/Clv:3
|
"A TGF-beta 3 isoform 1, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | | | |
organism-modification
|
|
PR:000036538 |
TGF-beta 3 isoform 1 cleaved 3 (mouse)
|
mTGFB3/iso:1/Clv:3
|
"A TGF-beta 3 isoform 1 cleaved 3 in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P17125-1, 30-298, 299-410." [PMID:1821856, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | | |
modification
|
|
PR:000018294 |
TGF-beta 3 proteolytic cleavage product
|
TGFB3/ClvPrd
|
"A TGF-beta 3 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000634 |
TGF-beta 3 isoform 1 cleaved 1
|
TGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 that has been processed by proteolytic cleavage and released from the latent complex. This form is the active mature peptide." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036536 |
TGF-beta 3 isoform 1 cleaved 1 (human)
|
hTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in human. UniProtKB:P10600-1, 301-412." [PMID:18243111, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036537 |
TGF-beta 3 isoform 1 cleaved 1 (mouse)
|
mTGFB3/iso:1/Clv:1
|
"A TGF-beta 3 isoform 1 cleaved 1 in mouse. UniProtKB:P17125-1, 299-410." [PMID:1821856, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000635 |
TGF-beta 3 isoform 1 cleaved 2
|
TGFB3/iso:1/Clv:2
|
"A TGF-beta 3 isoform 1, signal peptide removed form that has been processed by proteolytic cleavage to remove the C-terminal mature peptide. This chain is referred as to the latency associated peptide (LAP)." [PMID:11821050]
|
|
|
|
|
|
|
| | | | | | | | |
| | |
modification
|
|
PR:000000636 |
TGF-beta 3 isoform 1 cleaved 3
|
TGFB3/iso:1/Clv:3
|
"A TGF-beta 3 isoform 1, signal peptide removed form that has been processed by subsequent cleavage at the dibasic cleavage site rendering the latency associated peptide (LAP) and the mature protein non-covalently bound." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
|
organism-modification
|
|
PR:000036538 |
TGF-beta 3 isoform 1 cleaved 3 (mouse)
|
mTGFB3/iso:1/Clv:3
|
"A TGF-beta 3 isoform 1 cleaved 3 in mouse, in which the cleaved parts remain joined by disulfide bonds. UniProtKB:P17125-1, 30-298, 299-410." [PMID:1821856, PRO:CNA, PRO:DAN]
|
Yes |
|
|
|
