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Protein Ontology report - dengue virus genome polyprotein
PR:000036816 - http://purl.obolibrary.org/obo/PR_000036816
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036816   
  PRO namedengue virus genome polyprotein 
  Synonyms
PRO-Short-label: EXACT:DenV-polyprot
  Definition"A protein that is a translation product of the dengue virus serotype 2 genomic RNA or a 1:1 ortholog thereof." [PRO:ES] 
  CommentRequested by=IDODEN. The dengue virus contains a 10.7 kb single-stranded RNA genome of positive strand polarity with a type I cap at the 5' terminus. The RNA genome is translated into a large glycosylated polyprotein precursor with proteins that are arranged in the order NH2-C-prM-E-NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5-COOH. Proteolytic processing in the region of the structural proteins is mediated by a host cell signal peptidase that is located within the endoplasmic reticulum. [PMID:12297031, PRO:ES]. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 20                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification29                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000036816 dengue virus genome polyprotein
DenV-polyprot

organism-gene


PR:P07564 genome polyprotein (Dengue virus 2 Jamaica/1409/1983)
polyprot (DEN2J)

organism-gene


PR:P09866 genome polyprotein (Dengue virus 4 Dominica/814669/1981)
polyprot (DEN4D)

organism-gene


PR:P12823 genome polyprotein (Dengue virus 2 Puerto Rico/PR159-S1/1969)
polyprot (DEN2P)

organism-gene


PR:P14337 genome polyprotein (Dengue virus 2 Thailand/0168/1979)
polyprot (DEN28)

organism-gene


PR:P14340 genome polyprotein (Dengue virus 2 Thailand/NGS-C/1944)
polyprot (DEN2N)

organism-modification


PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944)
NS1 (DEN2N)
Yes
organism-modification


PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944)
NS2A (DEN2N)
Yes
organism-modification


PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944)
NS2B (DEN2N)
Yes
organism-modification


PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944)
NS3 (DEN2N)
Yes
organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
organism-modification


PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944)
NS4B (DEN2N)
Yes
organism-modification


PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944)
NS5 (DEN2N)
Yes
organism-modification


PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944)
prM (DEN2N)
Yes
organism-gene


PR:P17763 genome polyprotein (Dengue virus 1 Nauru/West Pac/1974)
polyprot (DEN1W)

organism-gene


PR:P27909 genome polyprotein (Dengue virus 1 Brazil/97-11/1997)
polyprot (DEN1B)

organism-gene


PR:P27915 genome polyprotein (Dengue virus 3 Philippines/H87/1956)
polyprot (DEN3P)

organism-gene


PR:P29990 genome polyprotein (Dengue virus 2 Thailand/16681/84)
polyprot (DEN26)

organism-modification


PR:000044757 M protein (Dengue virus 2 Thailand/16681/84)
M (DEN26)
Yes
organism-modification


PR:000044760 NS2A (Dengue virus 2 Thailand/16681/84)
NS2A (DEN26)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
organism-modification


PR:000044767 NS4B (Dengue virus 2 Thailand/16681/84)
NS4B (DEN26)
Yes
organism-modification


PR:000044769 prM (Dengue virus 2 Thailand/16681/84)
prM (DEN26)
Yes
organism-gene


PR:P29991 genome polyprotein (Dengue virus 2 16681-PDK53)
polyprot (DEN27)

organism-gene


PR:P33478 genome polyprotein (Dengue virus 1 Singapore/S275/1990)
polyprot (DEN1S)

organism-gene


PR:Q2YHF0 genome polyprotein (Dengue virus 4 Thailand/0348/1991)
polyprot (DEN4T)

organism-gene


PR:Q2YHF2 genome polyprotein (Dengue virus 4 Thailand/0476/1997)
polyprot (DEN4H)

organism-gene


PR:Q58HT7 genome polyprotein (Dengue virus 4 Philippines/H241/1956)
polyprot (DEN4P)

organism-gene


PR:Q5UB51 genome polyprotein (Dengue virus 3 Singapore/8120/1995)
polyprot (DEN3I)

organism-gene


PR:Q5UCB8 genome polyprotein (Dengue virus 4 Singapore/8976/1995)
polyprot (DEN4S)

organism-gene


PR:Q6YMS3 genome polyprotein (Dengue virus 3 Martinique/1243/1999)
polyprot (DEN3M)

organism-gene


PR:Q6YMS4 genome polyprotein (Dengue virus 3 Sri Lanka/1266/2000)
polyprot (DEN3S)

organism-gene


PR:Q99D35 genome polyprotein (Dengue virus 3 China/80-2/1980)
polyprot (DEN3C)

organism-gene


PR:Q9WDA6 genome polyprotein (Dengue virus 2 Peru/IQT2913/1996)
polyprot (DEN2Q)

modification


PR:000036817 dengue virus genome polyprotein, N-glycosylated form
DenV-polyprot/NGlycoAsn+

modification


PR:000036818 dengue virus genome polyprotein proteolytic cleavage product
DenV-polyprot/ClvPrd

modification


PR:000036819 capsid protein C
DenV-C

modification


PR:000036820 pr protein
DenV-pr

modification


PR:000036821 M protein
DenV-M

organism-modification


PR:000044757 M protein (Dengue virus 2 Thailand/16681/84)
M (DEN26)
Yes
modification


PR:000036822 E protein
DenV-E

Yes
modification


PR:000036824 NS1
DenV-NS1

Yes
modification


PR:000037000 NS1, with complex sugar attached
DenV-NS1/sugar(+)

Yes
modification


PR:000037001 NS1, without complex sugar attached
DenV-NS1/sugar(-)

Yes
organism-modification


PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944)
NS1 (DEN2N)
Yes
modification


PR:000036825 NS2A
DenV-NS2A

organism-modification


PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944)
NS2A (DEN2N)
Yes
organism-modification


PR:000044760 NS2A (Dengue virus 2 Thailand/16681/84)
NS2A (DEN26)
Yes
modification


PR:000036826 NS2A-alpha
DenV-NS2Aalpha

modification


PR:000036827 NS2B
DenV-NS2B

Yes
organism-modification


PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944)
NS2B (DEN2N)
Yes
modification


PR:000036828 NS3
DenV-NS3

Yes
organism-modification


PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944)
NS3 (DEN2N)
Yes
modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036832 precursor of NS4B
DenV-preNS4B

modification


PR:000036833 NS4B
DenV-NS4B

organism-modification


PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944)
NS4B (DEN2N)
Yes
organism-modification


PR:000044767 NS4B (Dengue virus 2 Thailand/16681/84)
NS4B (DEN26)
Yes
modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036833 NS4B
DenV-NS4B

organism-modification


PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944)
NS4B (DEN2N)
Yes
organism-modification


PR:000044767 NS4B (Dengue virus 2 Thailand/16681/84)
NS4B (DEN26)
Yes
modification


PR:000036834 precursor of NS5
DenV-preNS5

modification


PR:000036835 NS5
DenV-NS5

organism-modification


PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944)
NS5 (DEN2N)
Yes
modification


PR:000036840 NS4A-NS4B-NS5
DenV-NS4AB5

modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036835 NS5
DenV-NS5

organism-modification


PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944)
NS5 (DEN2N)
Yes
modification


PR:000036836 C-prM
DenV-CprM

modification


PR:000036819 capsid protein C
DenV-C

modification


PR:000036837 prM
DenV-prM

Yes
modification


PR:000036820 pr protein
DenV-pr

modification


PR:000036821 M protein
DenV-M

organism-modification


PR:000044757 M protein (Dengue virus 2 Thailand/16681/84)
M (DEN26)
Yes
organism-modification


PR:000044769 prM (Dengue virus 2 Thailand/16681/84)
prM (DEN26)
Yes
organism-modification


PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944)
prM (DEN2N)
Yes
modification


PR:000036837 prM
DenV-prM

Yes
modification


PR:000036820 pr protein
DenV-pr

modification


PR:000036821 M protein
DenV-M

organism-modification


PR:000044757 M protein (Dengue virus 2 Thailand/16681/84)
M (DEN26)
Yes
organism-modification


PR:000044769 prM (Dengue virus 2 Thailand/16681/84)
prM (DEN26)
Yes
organism-modification


PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944)
prM (DEN2N)
Yes
modification


PR:000036838 NS12345
DenV-NS12345

modification


PR:000036826 NS2A-alpha
DenV-NS2Aalpha

modification


PR:000036827 NS2B
DenV-NS2B

Yes
organism-modification


PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944)
NS2B (DEN2N)
Yes
modification


PR:000036839 NS345
DenV-NS345

modification


PR:000036828 NS3
DenV-NS3

Yes
organism-modification


PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944)
NS3 (DEN2N)
Yes
modification


PR:000036840 NS4A-NS4B-NS5
DenV-NS4AB5

modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036873 NS2B-NS3 polyprotein precursor
DenV-NS2B3

modification


PR:000036998 NS1-NS2A
DenV-NS12A

modification


PR:000036824 NS1
DenV-NS1

Yes
modification


PR:000037000 NS1, with complex sugar attached
DenV-NS1/sugar(+)

Yes
modification


PR:000037001 NS1, without complex sugar attached
DenV-NS1/sugar(-)

Yes
organism-modification


PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944)
NS1 (DEN2N)
Yes
modification


PR:000036825 NS2A
DenV-NS2A

organism-modification


PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944)
NS2A (DEN2N)
Yes
organism-modification


PR:000044760 NS2A (Dengue virus 2 Thailand/16681/84)
NS2A (DEN26)
Yes
modification


PR:000036839 NS345
DenV-NS345

modification


PR:000036828 NS3
DenV-NS3

Yes
organism-modification


PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944)
NS3 (DEN2N)
Yes
modification


PR:000036840 NS4A-NS4B-NS5
DenV-NS4AB5

modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036840 NS4A-NS4B-NS5
DenV-NS4AB5

modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036873 NS2B-NS3 polyprotein precursor
DenV-NS2B3

modification


PR:000036998 NS1-NS2A
DenV-NS12A

modification


PR:000036824 NS1
DenV-NS1

Yes
modification


PR:000037000 NS1, with complex sugar attached
DenV-NS1/sugar(+)

Yes
modification


PR:000037001 NS1, without complex sugar attached
DenV-NS1/sugar(-)

Yes
organism-modification


PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944)
NS1 (DEN2N)
Yes
modification


PR:000036825 NS2A
DenV-NS2A

organism-modification


PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944)
NS2A (DEN2N)
Yes
organism-modification


PR:000044760 NS2A (Dengue virus 2 Thailand/16681/84)
NS2A (DEN26)
Yes
modification


PR:000036822 E protein
DenV-E

Yes
modification


PR:000036836 C-prM
DenV-CprM

modification


PR:000036819 capsid protein C
DenV-C

modification


PR:000036837 prM
DenV-prM

Yes
modification


PR:000036820 pr protein
DenV-pr

modification


PR:000036821 M protein
DenV-M

organism-modification


PR:000044757 M protein (Dengue virus 2 Thailand/16681/84)
M (DEN26)
Yes
organism-modification


PR:000044769 prM (Dengue virus 2 Thailand/16681/84)
prM (DEN26)
Yes
organism-modification


PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944)
prM (DEN2N)
Yes
modification


PR:000036838 NS12345
DenV-NS12345

modification


PR:000036826 NS2A-alpha
DenV-NS2Aalpha

modification


PR:000036827 NS2B
DenV-NS2B

Yes
organism-modification


PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944)
NS2B (DEN2N)
Yes
modification


PR:000036839 NS345
DenV-NS345

modification


PR:000036828 NS3
DenV-NS3

Yes
organism-modification


PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944)
NS3 (DEN2N)
Yes
modification


PR:000036840 NS4A-NS4B-NS5
DenV-NS4AB5

modification


PR:000036841 NS4AB
DenV-NS4AB

modification


PR:000036830 NS4A
DenV-NS4A

organism-modification


PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944)
NS4A (DEN2N)
Yes
organism-modification


PR:000044764 NS4A (Dengue virus 2 Thailand/16681/84)
NS4A (DEN26)
Yes
modification


PR:000036842 2KNS4B
DenV-2KNS4B

modification


PR:000036831 2K
DenV-2K

organism-modification


PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944)
2K (DEN2N)
Yes
modification


PR:000036843 NS4B-NS5
DenV-NS4B5

modification


PR:000036873 NS2B-NS3 polyprotein precursor
DenV-NS2B3

modification


PR:000036998 NS1-NS2A
DenV-NS12A

modification


PR:000036824 NS1
DenV-NS1

Yes
modification


PR:000037000 NS1, with complex sugar attached
DenV-NS1/sugar(+)

Yes
modification


PR:000037001 NS1, without complex sugar attached
DenV-NS1/sugar(-)

Yes
organism-modification


PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944)
NS1 (DEN2N)
Yes
modification


PR:000036825 NS2A
DenV-NS2A

organism-modification


PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944)
NS2A (DEN2N)
Yes
organism-modification


PR:000044760 NS2A (Dengue virus 2 Thailand/16681/84)
NS2A (DEN26)
Yes
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DenV-polyprot forms found in complexes   

DenV-polyprot Component
 Complexes
PR:000036822 DenV-E PR:000036823 prM-E complex
PR:000036999 E protein dimer
PR:000036824 DenV-NS1 PR:000037002 NS1 dimer
PR:000036827 DenV-NS2B PR:000036829 NS2B-NS3 complex
PR:000036828 DenV-NS3 PR:000036829 NS2B-NS3 complex
PR:000036837 DenV-prM PR:000036823 prM-E complex
PR:000037000 DenV-NS1/sugar(+) PR:000037003 NS1 dimer, with complex sugar attached
PR:000037005 NS1 hexamer, with complex sugar attached
PR:000037001 DenV-NS1/sugar(-) PR:000037004 NS1 dimer, without complex sugar unattached
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044757 M (DEN26)
UniProtKB:P29990, 206-280		 acts_upstream_of_or_withinGO:0006955 immune response PMID:14963133
located_inGO:0019031 viral envelope PMID:14963133
PR:000044758 NS1 (DEN2N)
UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160		 acts_upstream_of_or_withinGO:0019079 viral genome replication PMID:23408612
GO:0097281 immune complex formation PMID:23408612
located_inGO:0019034 viral replication complex PMID:23408612
PR:000044759 NS2A (DEN2N)
UniProtKB:P14340, 1128-1345		 acts_upstream_of_or_withinGO:0019068 virion assembly PMID:23408612
GO:0019076 viral release from host cell PMID:23408612
GO:0019079 viral genome replication PMID:23408612
located_inGO:0019034 viral replication complex PMID:23408612
PR:000044760 NS2A (DEN26)
UniProtKB:P29990, 1128-1345		 acts_upstream_of_or_withinGO:0060339 negative regulation of type I interferon-mediated signaling pathway PMID:14612562
PR:000044761 NS2B (DEN2N)
UniProtKB:P14340, 1346-1475		 acts_upstream_of_or_withinGO:1900005 positive regulation of serine-type endopeptidase activity PMID:10744671
enablescontributes_to GO:0008236 serine-type peptidase activity PMID:10744671
PR:000044762 NS3 (DEN2N)
UniProtKB:P14340, 1476-2093		 acts_upstream_of_or_withinGO:0019082 viral protein processing PMID:10744671
enablesGO:0003724 RNA helicase activity PMID:10744671
GO:0008236 serine-type peptidase activity PMID:10744671
GO:0017111 ribonucleoside triphosphate phosphatase activity PMID:10744671
PR:000044763 NS4A (DEN2N)
UniProtKB:P14340, 2094-2220		 acts_upstream_of_or_withinGO:0019079 viral genome replication PMID:17276984
located_inGO:0019034 viral replication complex PMID:17276984
PR:000044764 NS4A (DEN26)
UniProtKB:P29990, 2094-2220		 acts_upstream_of_or_withinGO:0060339 negative regulation of type I interferon-mediated signaling pathway PMID:14612562
PR:000044765 2K (DEN2N)
UniProtKB:P14340, 2221-2243		 acts_upstream_of_or_withinGO:0045051 protein insertion into ER membrane by internal uncleaved signal-anchor sequence PMID:17276984
enablesGO:0043495 protein-membrane adaptor activity PMID:21810535
located_inGO:0016020 membrane PMID:21810535
PR:000044766 NS4B (DEN2N)
UniProtKB:P14340, 2244-2491		 acts_upstream_of_or_withinGO:0019079 viral genome replication PMID:21810535
located_inGO:0019034 viral replication complex PMID:21810535
PR:000044767 NS4B (DEN26)
UniProtKB:P29990, 2244-2491		 acts_upstream_of_or_withinGO:0039563 symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity PMID:14612562
PR:000044768 NS5 (DEN2N)
UniProtKB:P14340, 2492-3391		 acts_upstream_of_or_withinGO:0001510 RNA methylation PMID:21810535
GO:0019079 viral genome replication PMID:21810535
GO:0042783 symbiont-mediated evasion of host immune response PMID:21810535
enablesGO:0003968 RNA-directed RNA polymerase activity PMID:21810535
GO:0008168 methyltransferase activity PMID:21810535
GO:0070568 guanylyltransferase activity PMID:23408612
located_inGO:0019034 viral replication complex PMID:21810535
PR:000044769 prM (DEN26)
UniProtKB:P29990, 115-280, Asn-183, MOD:00160		 acts_upstream_of_or_withinGO:0015031 protein transport PMID:14963133
GO:0019068 virion assembly PMID:14963133
enablesGO:0044183 protein folding chaperone PMID:14963133
PR:000044770 prM (DEN2N)
UniProtKB:P14340, 115-280, Asn-183, MOD:00160		 acts_upstream_of_or_withinGO:0006955 immune response PMID:8429301
located_inGO:0019031 viral envelope PMID:8429301