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Protein Ontology Report - TRADD:TRAF2:RIP1:FADD:caspase-8 complex (human)

PR:000028435 - http://purl.obolibrary.org/obo/PR_000028435
Ontology Information
PRO ID PR:000028435 Show OBO stanza
PRO name TRADD:TRAF2:RIP1:FADD:caspase-8 complex (human)
Definition A death-inducing signaling complex that is composed of one molecule of caspase-8 (human), three molecules of TNF receptor-associated factor 2, initiator methionine removed form (human), two molecules of FAS-associated death domain protein (human), one molecule of receptor-interacting serine/threonine-protein kinase 1 (human), and three molecules of tumor necrosis factor receptor type 1-associated DEATH domain protein (human). [PRO:DAN, PRO:PDE, Reactome:R-HSA-140976]
PRO Category organism-complex
Parent GO:0031264 death-inducing signaling complex
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000028435 PR:Q15628 tumor necrosis factor receptor type 1-associated DEATH domain protein (human) hTRADD A tumor necrosis factor receptor type 1-associated DEATH domain protein that is encoded in the genome of human. [PRO:DNx] 3
PR:Q13546 receptor-interacting serine/threonine-protein kinase 1 (human) hRIPK1 A receptor-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human. [PRO:DNx] 1
PR:Q14790 caspase-8 (human) hCASP8 A caspase-8 that is encoded in the genome of human. [PRO:DNx] 1
PR:Q13158 FAS-associated death domain protein (human) hFADD A FAS-associated death domain protein that is encoded in the genome of human. [PRO:DNx] 2
PR:000028382 TNF receptor-associated factor 2, initiator methionine removed form (human) hTRAF2/InitMet- A TNF receptor-associated factor 2, initiator methionine removed form in human. Example: UniProtKB:Q12933-1, 2-501. [PRO:DNx] 1


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