PRO Entry Report - PR:000036848

Protein Ontology Report - CD14/iso:1/Clv:2

PR:000036848 - http://purl.obolibrary.org/obo/PR_000036848

Protein Forms Complex Annotations

Ontology Information

PRO ID

PR:000036848 Show OBO stanza / PAF

PRO name

CD14 molecule isoform 1 cleaved 2

Synonyms

PRO-short-label:

EXACT:

CD14/iso:1/Clv:2

Definition

A CD14 molecule isoform 1, signal peptide removed form that lacks the propeptide. Example: UniProtKB:P08571-1, 20-345. [PRO:DAN]

PRO Category

modification

Parent

PR:000025460 CD14 molecule isoform 1, signal peptide removed form

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

CD14/iso:1/Clv:2 forms found in complexes

CD14/iso:1/Clv:2 Component	Complexes
PR:000002147 CD14/iso:1/Clv:2/soluble	PR:000025498 lipopolysaccharide receptor complex 4
PR:000002147 CD14/iso:1/Clv:2/soluble	PR:000025496 lipopolysaccharide receptor complex 2
PR:000002149 CD14/iso:1/Clv:2/anchored	PR:000025493 LPS:GPI-anchored CD14 complex
PR:000002149 CD14/iso:1/Clv:2/anchored	PR:000025497 lipopolysaccharide receptor complex 3
PR:000002149 CD14/iso:1/Clv:2/anchored	PR:000025495 lipopolysaccharide receptor complex 1
PR:000035702 hCD14/iso:1/Clv:2/anchored	PR:000037464 LPS:GPI-anchored CD14 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored	PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored	PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored	PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored	PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000035702 hCD14/iso:1/Clv:2/anchored	PR:000025773 lipopolysaccharide receptor complex 3 (human)
PR:000035703 hCD14/iso:1/Clv:2/soluble	PR:000037479 lipopolysaccharide receptor complex 4 (human)
PR:000035703 hCD14/iso:1/Clv:2/soluble	PR:000037463 LPS:secreted CD14 alpha (human)
PR:000037470 mCD14/iso:1/Clv:2/anchored	PR:000037468 LPS:GPI-anchored CD14 complex (mouse)
PR:000037470 mCD14/iso:1/Clv:2/anchored	PR:000037476 lipopolysaccharide receptor complex 3 (mouse)
PR:000037480 hCD14/iso:1/Clv:2	PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037480 hCD14/iso:1/Clv:2	PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037480 hCD14/iso:1/Clv:2	PR:000036135 TIRAP:PIP2:activated TLR4 complex (human)
PR:000037480 hCD14/iso:1/Clv:2	PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human)

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000036848 CD14/iso:1/Clv:2	acts_upstream_of_or_within	GO:0032147 activation of protein kinase activity	MGI:3836081, PMID:18854309
	located_in	GO:0016020 membrane	MGI:3836081, PMID:18854309
	located_in	GO:0005737 cytoplasm	MGI:3836081, PMID:18854309

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0016020 membrane	PR:000036848 CD14/iso:1/Clv:2	MGI:3836081, PMID:18854309
GO:0005737 cytoplasm	PR:000036848 CD14/iso:1/Clv:2	MGI:3836081, PMID:18854309

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